Histamine N-methyltransferase Modulates Human Bronchial Smooth Muscle Contraction
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چکیده
منابع مشابه
Histamine N-methyltransferase Modulates Human Bronchial Smooth Muscle Contraction
To elucidate the modulatory role of histamine-degrading enzymes in airway constrictor responses, human bronchial strips were studied under isometric conditions in vitro. Pretreatment of tissues with the histamine N-methyltransferase (HMT) inhibitor SKF 91488 specifically potentiated the contractile responses to histamine, causing a leftward displacement of the concentration response curves, whe...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 1994
ISSN: 0962-9351,1466-1861
DOI: 10.1155/s0962935194000153